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Obstetrician-gynecologist

State of metabolic processes and ways to improve them in premenopausal women due to the Life Extension Strategy

Increasing the duration and improving the quality of life of older age groups is a significant problem of modern medicine. Metabolic disorders in the form of diabetes mellitus type II and atherogenic dyslipidemia lead to a significant level of cardiovascular complications. It is known that the appointment of hormone replacement therapy is not able to...
Urologist

Safety and efficacy of intravesical administration for symptom control in chronic cystopathy

INTRODUCTION: Chronic cystopathy is a widespread pathology. Intravesical hyaluronic acid (instillation) is one of the treatment options for cystopathies. This study analyzed safety and efficacy of intravesical hyaluronic acid instillations in patients with symptoms of urinary blabber disease. MATERIALS AND METHODS: A population comprising 32 patients received intravesical instillations with ...
Urologist

Intravesical instillation of high molecular weight sodium hyaluronate in radiation‑induced cystitis: a prospective pilot study

Purpose. To assess the efficacy and safety of intravesical instillation of high molecular weight sodium hyaluronate (HMW- HA) for the treatment of radiation-induced cystitis. Methods. This prospective cohort study was conducted in seven centers in France. Eligible patients with radiation-induced cystitis were recruited between April 2020 and March 2021. A ...
The anesthesiologist and specialist on medical emergency conditions

Соchrane Database of Systematic Rewiews. Edaravone for acute ischaemic stroke.

Edaravone is a neuroprotective agent, and several studies have suggested that it may be beneficial in acute ischaemic stroke. Objectives. To assess the efficacy and safety of edaravone for acute ischaemic stroke. Main results. Authors included three trials. All three included trials were of edaravone plus another treatment compared with the other treatment alone. The...
Endocrinologist

Pathogenetic pancreoprotection in diabetic ketoacidosis

Diabetes is an important medical and social problem, as it develops in each of the 11 adult inhabitants of the planet. In the complicated course of diabetes mellitus, ketoacidosis develops, which is the most common manifestation of acute hyperglycemia in people with both types of diabetes mellitus. The purpose of this study is to systematize...
The anesthesiologist and specialist on medical emergency conditions, Orthopaedic Trauma, Surgeon, Obstetrician-gynecologist

Modern approaches to the correction of hemodynamic disorders in patients with severe combined trauma

Background. Selection of a rational program of infusion therapy in severe trauma remains a current problem. Crystalloid solutions are used as the principal infusion media, but literature on the effects of balanced multicomponent solutions on hemodynamic profiles in patients with severe trauma is virtually absent. Objective: to investigate the possibilities for correction of ...
General practitioner

Rheosorbilact: detoxifying properties and effects of this drug on hemostasis

Summary. The administration of Rheosorbilact in the form of intravenous infusions in the setting of combined therapy of patients with purulent-septic diseases, isolated craniocerebral injuries, pneumonias, and surgical interventions for the internal carotid artery reconstruction exerts a pronounced detoxification effect, which manifests itself in the reduction in concentration of middle molecules and lipid ...
Gastroenterologist

Pilot study of anxiolytic drug Lodixem in patients with acute decompensed heart failure

Anxiety disorders often accompany the course of cardiovascular disease and become more pronounced as they progress. Anxiety is also a frequent companion of patients with heart failure (HF). In a recent meta-analysis of 38 studies by K. Easton et al. (2015) estimated that 32% of patients with HF experience an increased level of anxiety, and...
Cardiologist

Patients with cardiovascular diseases – diagnosis and correction of iron deficiency conditions

The latent iron deficiency among the adult population, even in European countries, is 30-40%. At the same time very often, iron deficiency is confused with anemia. That is why in this context it is appropriate to draw a parallel with the captain of the Titanic, who saw only the tip of the iceberg, and therefore...
General practitioner

Efficacy of moxifloxacin in the treatment of communityacquired pneumonia

The review article presents the results of domestic and international studies of the use of fluoroquinolone 4th generation Moxifloxacin in the treatment of community-acquired pneumonia and pneumonia caused by SARS-CoV-2. Analysis of the clinical use of moxifloxacin in the treatment of infectious complications of the respiratory tract indicates its high efficiency and bioavailability, low risk...
General practitioner

Healthy nephrone — a guaranty of stable blood pressure

Chronic kidney disease is one of the most common diseases in the world. Along with damage to the kidneys, the disease carries great risks for the cardiovascular, endocrine and other systems of the body. The review presents the latest views and research data on this problem, as well as modern therapeutic solutions for the comprehensive...
Obstetrician-gynecologist

Prevention of surgical site infection in women with high risk and comorbidity

Purpose — to analyze the effectiveness of antiseptics with decamethoxine for the prevention of surgical wound infection in women at risk: with autoimmune pathology, obesity. Materials and methods. An analysis of the English literature to identify global trends in the incidence of cesarean section, the spread of autoimmune diseases, obesity, analysis of antiseptics prevention of...
Obstetrician-gynecologist

Metabolic regulation in mitochondria as a prospective way of body rejuvenation

Scientists around the world are looking for ways to achieve high-quality and active longevity. The complexity of these searches is associated with the lack of unified concept of aging mechanisms, the problem of extrapolating the results of studies of geroprotectors from model organisms to humans. Therefore, modern medicine can only slow down the aging process...
Cardiologist

What should a practitioner know about endothelial dysfunction?

Abstract: In this paper updated value of endothelial dysfunction (ED) in the pathogenesis of cardiovascular system diseases. Its main manifestation is a violation of the bioavailability of nitric oxide (NO). The only substrate for NO synthesis is L-arginine. Representative of this class of drugs is Tivortin containing the optimal daily concentration of L-arginine. Key words:...
Endocrinologist

Therapy patients with acute myocardial infarction – treatment with L-carnitine and L-arginine complex

The aim – to evaluate the effectiveness l-carnitine and l-arginine complex in addition to standard therapy for patients with acute myocardial infarction (AMI). Materials and methods. The study included 60 patients whose average age was 48.9±19.2 years, with a verified diagnosis of AMI followed percutaneous coronary intervention. The observation period lasted 6 weeks. Patients ...