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Effect of a Novel Free Radical Scavenger, Edaravone (MCI-186), on Acute Brain Infarction

Otomo Edaravone, a novel free radical scavenger, demonstrates neuroprotective effects by inhibiting vascular endothelial cell injury and ameliorating neuronal damage in ischemic brain models. The present study was undertaken to verify its therapeutic efficacy following acute ischemic stroke. We performed a multicenter, randomized, placebo-controlled, double-blind study on acute ischemic stroke patients ...

Acute ischemic stroke: revealing the maximum possibilities of pharmacotherapy

Гострий ішемічний інсульт Трускавець ZU_12_2019_ Materials of the XXI International Scientific and Practical Conference “Interdisciplinary Issues in Modern Neurology”, April 22-24, Truskavets, Ukraine. Considerable attention was paid to the problematic aspects of management of patients with acute ischemic stroke. Within the framework of separate scientific symposium was held a discussion about the possibilities of modern ...

Sorbilact® as a mean of pharmacological correction of postoperative ileus

Postoperative ileus (POI) occurs after many surgical interventions, but most often after abdominal operations — with a frequency of 10–30 %. This complication increases postoperative morbidity, duration of hospitalization and cost of treatment. In the Cochrane systematic review, it was shown that none of the routinely used prokinetic drugs (neostigmine, ...

Digest about the use of edaravone for acute ischemic stroke (2015-2019)

Дайджест малюнок Effect of Edaravone on Favorable Outcome in Patients with Acute Cerebral Large Vessel Occlusion: Subanalysis of RESCUE-Japan Registry (Neurol. Med. Chir. (Tokyo), 2015 March; 55(3)) Edaravone with and without .6 Mg/Kg Alteplase within 4.5 Hours after Ischemic Stroke: A Prospective Cohort Study (PROTECT4.5) (Journal of Stroke and Cerebrovascular Diseases, 2017, ...

2019 is the year of the fight against thrombocytopenia

blood drop In 2019, «Yuria-Pharm» announced the year for the fight against thrombocytopenia. Regarding this company, an appropriate program was started, in which cancer and hematologic departments throughout Ukraine received recombinant human thrombopoietin (EMAPLUG) as charitable aid for patients with thrombocytopenia. Many readers of the medical newspaper “News of Medicine and Pharmacy” ...
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