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The role of L-arginine in the treatment of cardiovascular diseases: the focus is on the choice of effective dose

L-arginine is a conditionally essential amino acid that was first isolated in 1886 by E. Schulze and E. Steiger, and its structure was established by E. Schulze and E. Winterstei in 1897 [1]. L-arginine is used several times ways for the synthesis of protein and low molecular weight bioactive substances ...

Acute ischemic stroke: revealing the maximum possibilities of pharmacotherapy

Гострий ішемічний інсульт Трускавець ZU_12_2019_

Materials of the XXI International Scientific and Practical Conference “Interdisciplinary Issues in Modern Neurology”, April 22-24, Truskavets, Ukraine. Considerable attention was paid to the problematic aspects of management of patients with acute ischemic stroke. Within the framework of separate scientific symposium was held a discussion about the possibilities of modern ...

Acute Kidney Injury and Edaravone in Acute Ischemic Stroke: The Fukuoka Stroke Registry

Background: A free radical scavenger, edaravone, which has been used for the treatment of ischemic stroke, was reported to cause acute kidney injury (AKI) as a fatal adverse event. The aim of the present study was to clarify whether edaravone is associated with AKI in patients with acute ischemic stroke. ...

Stress hyperglycemia: discussion of ways to eliminate it with the help of sugar alcohols

The literature review considers the prospect of resuming active use of sugar alcohols in the practice of intensive care. The information is focused on the characteristics of the metabolism and the expected effects of sugar five-carbon alcohol xylitol. The feasibility of using xylitol solutions is justified by reducing the risk ...

Sorbilact® as a mean of pharmacological correction of postoperative ileus

Postoperative ileus (POI) occurs after many surgical interventions, but most often after abdominal operations — with a frequency of 10–30 %. This complication increases postoperative morbidity, duration of hospitalization and cost of treatment. In the Cochrane systematic review, it was shown that none of the routinely used prokinetic drugs (neostigmine, ...

The search for new methods and drugs to struggle with cerebral stroke and its complications

The scientific-practical conference “Opportunities and Achievements of Modern Pharmacotherapy in the Practice of a Neurologist” held in Kharkov on March 14-15, 2019. It was organized by Association of Neurologists, Psychiatrists and Narcologists of Ukraine, Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine, Kharkiv ...

Digest about the use of edaravone for acute ischemic stroke (2015-2019)

Effect of Edaravone on Favorable Outcome in Patients with Acute Cerebral Large Vessel Occlusion: Subanalysis of RESCUE-Japan Registry (Neurol. Med. Chir. (Tokyo), 2015 March; 55(3)) Edaravone with and without .6 Mg/Kg Alteplase within 4.5 Hours after Ischemic Stroke: A Prospective Cohort Study (PROTECT4.5) (Journal of Stroke and Cerebrovascular Diseases, 2017, ...

2019 is the year of the fight against thrombocytopenia

In 2019, «Yuria-Pharm» announced the year for the fight against thrombocytopenia. Regarding this company, an appropriate program was started, in which cancer and hematologic departments throughout Ukraine received recombinant human thrombopoietin (EMAPLUG) as charitable aid for patients with thrombocytopenia. Many readers of the medical newspaper “News of Medicine and Pharmacy” ...

The possibilities of using combination therapy in patients with dyscirculatory encephalopathy

Abstract.The article presents the results of a clinical study on the efficiency and tolerability of the combined use of drugs Neurocytin and Latren, solutions in comparison with the drug Neurocytin, solution, produced by Yuria Pharm Ltd. in patients with stage II arterial hypertension (AH) and atherosclerosis. Studies were conducted in ...

Treatment of Recombinant Human Thrombopoietin in Thrombocytopenia after Chemotherapy of Acute Leukemia

After chemotherapy, the patients with acute leukemia often accompany with severe thrombocytopenia, and it is difficult to be prevented and treated. For a long time, platelet transfusion is always the standard therapeutic method for severe thrombocytopenia with definite efficacy. But the platelets have short storage time, nervous sources, and can ...