Extensive use of the polarizing solution (GIK®) is attributed to the effect of switching metabolism of damaged myocardium from wasteful oxidation of free fatty acids to glucose, which is more favourable energetically in the presence of hypoxia.
– Normalizes myocardial metabolism in the presence of ischemia;
– Has antiarrhythmic effect;
– Reduces increased sensitivity to cardiac glycosides; and
– Reduces their cardiotoxic effect.